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Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma
AIMS: Deleted in liver cancer 1 (DLC1), a member of RhoGTPase activating protein (GAP) family, is known to have suppressive activities in tumorigenicity and cancer metastasis. However, the underlying molecular mechanisms of how DLC1 suppresses cell motility have not been fully elucidated. Rho-kinase...
Autores principales: | Wong, Carmen Chak-Lui, Wong, Chun-Ming, Ko, Frankie Chi-Fat, Chan, Lo-Kong, Ching, Yick-Pang, Yam, Judy Wai-Ping, Ng, Irene Oi-lin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464714/ https://www.ncbi.nlm.nih.gov/pubmed/18648664 http://dx.doi.org/10.1371/journal.pone.0002779 |
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