Mitochondria, PPARs, and Cancer: Is Receptor-Independent Action of PPAR Agonists a Key?

Before the discovery of peroxisome proliferator activated receptors (PPARs), it was well known that certain drugs considered as classical PPAR-alpha agonists induced hepatocarcinoma or peroxisome proliferation in rodents. These drugs were derivatives of fibric acid, and they included clofibrate, bez...

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Detalles Bibliográficos
Autores principales: Scatena, Roberto, Bottoni, Patrizia, Giardina, Bruno
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464819/
https://www.ncbi.nlm.nih.gov/pubmed/18645611
http://dx.doi.org/10.1155/2008/256251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464819/
https://www.ncbi.nlm.nih.gov/pubmed/18645611
http://dx.doi.org/10.1155/2008/256251

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