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Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia
Friedreich ataxia (FA) is a progressive neurodegenerative disease caused by expansion of a trinucleotide repeat within the first intron of the gene that encodes frataxin. In our study, we investigated the regulation of frataxin expression by iron and demonstrated that frataxin mRNA levels decrease s...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465796/ https://www.ncbi.nlm.nih.gov/pubmed/18424449 http://dx.doi.org/10.1093/hmg/ddn127 |