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Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia

Friedreich ataxia (FA) is a progressive neurodegenerative disease caused by expansion of a trinucleotide repeat within the first intron of the gene that encodes frataxin. In our study, we investigated the regulation of frataxin expression by iron and demonstrated that frataxin mRNA levels decrease s...

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Detalles Bibliográficos
Autores principales:	Li, Kuanyu, Besse, Edward K., Ha, Dung, Kovtunovych, Gennadiy, Rouault, Tracey A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465796/ https://www.ncbi.nlm.nih.gov/pubmed/18424449 http://dx.doi.org/10.1093/hmg/ddn127

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