TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21(Cip1 )or Rb status

BACKGROUND: TGFβ has pleiotropic effects that range from regulation of proliferation and apoptosis to morphological changes and epithelial-mesenchymal transition (EMT). Some evidence suggests that these effects may be interconnected. We have recently reported that P53, P21(Cip1 )and pRB, three criti...

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Detalles Bibliográficos
Autores principales: Sheahan, Sharon, Bellamy, Christopher O, Harland, Stephen N, Harrison, David J, Prost, Sandrine
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467431/
https://www.ncbi.nlm.nih.gov/pubmed/18611248
http://dx.doi.org/10.1186/1471-2407-8-191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467431/
https://www.ncbi.nlm.nih.gov/pubmed/18611248
http://dx.doi.org/10.1186/1471-2407-8-191

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