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TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21(Cip1 )or Rb status
BACKGROUND: TGFβ has pleiotropic effects that range from regulation of proliferation and apoptosis to morphological changes and epithelial-mesenchymal transition (EMT). Some evidence suggests that these effects may be interconnected. We have recently reported that P53, P21(Cip1 )and pRB, three criti...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467431/ https://www.ncbi.nlm.nih.gov/pubmed/18611248 http://dx.doi.org/10.1186/1471-2407-8-191 |