Laboratory evolution of Pyrococcus furiosus alcohol dehydrogenase to improve the production of (2S,5S)-hexanediol at moderate temperatures

There is considerable interest in the use of enantioselective alcohol dehydrogenases for the production of enantio- and diastereomerically pure diols, which are important building blocks for pharmaceuticals, agrochemicals and fine chemicals. Due to the need for a stable alcohol dehydrogenase with ac...

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Detalles Bibliográficos
Autores principales: Machielsen, Ronnie, Leferink, Nicole G. H., Hendriks, Annemarie, Brouns, Stan J. J., Hennemann, Hans-Georg, Dauβmann, Thomas, van der Oost, John
Formato: Texto
Lenguaje:English
Publicado: Springer Japan 2008
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467505/
https://www.ncbi.nlm.nih.gov/pubmed/18452026
http://dx.doi.org/10.1007/s00792-008-0164-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467505/
https://www.ncbi.nlm.nih.gov/pubmed/18452026
http://dx.doi.org/10.1007/s00792-008-0164-8

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