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A knowledge-driven approach for crystallographic protein model completion

One of the most cumbersome and time-demanding tasks in completing a protein model is building short missing regions or ‘loops’. A method is presented that uses structural and electron-density information to build the most likely conformations of such loops. Using the distribution of angles and dihed...

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Detalles Bibliográficos
Autores principales: Joosten, Krista, Cohen, Serge X., Emsley, Paul, Mooij, Wijnand, Lamzin, Victor S., Perrakis, Anastassis
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2467521/
https://www.ncbi.nlm.nih.gov/pubmed/18391408
http://dx.doi.org/10.1107/S0907444908001558