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Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA

Decreased blood–brain barrier (BBB) efflux function of the P-glycoprotein (P-gp) transport system could facilitate the accumulation of toxic compounds in the brain, increasing the risk of neurodegenerative pathology such as Parkinson’s disease (PD). This study investigated in vivo BBB P-gp function...

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Detalles Bibliográficos
Autores principales: Bartels, A. L., Willemsen, A. T. M., Kortekaas, R., de Jong, B. M., de Vries, R., de Klerk, O., van Oostrom, J. C. H., Portman, A., Leenders, K. L.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2468317/
https://www.ncbi.nlm.nih.gov/pubmed/18265929
http://dx.doi.org/10.1007/s00702-008-0030-y