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Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA
Decreased blood–brain barrier (BBB) efflux function of the P-glycoprotein (P-gp) transport system could facilitate the accumulation of toxic compounds in the brain, increasing the risk of neurodegenerative pathology such as Parkinson’s disease (PD). This study investigated in vivo BBB P-gp function...
Autores principales: | Bartels, A. L., Willemsen, A. T. M., Kortekaas, R., de Jong, B. M., de Vries, R., de Klerk, O., van Oostrom, J. C. H., Portman, A., Leenders, K. L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2468317/ https://www.ncbi.nlm.nih.gov/pubmed/18265929 http://dx.doi.org/10.1007/s00702-008-0030-y |
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