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CXCR2 chemokine receptor antagonism enhances DOP opioid receptor function via allosteric regulation of the CXCR2–DOP receptor heterodimer
Opioid agonists have a broad range of effects on cells of the immune system, including modulation of the inflammatory response, and opioid and chemokine receptors are co-expressed by many white cells. Hetero-oligomerization of the human DOP opioid and chemokine CXCR2 receptors could be detected foll...
Autores principales: | Parenty, Geraldine, Appelbe, Shirley, Milligan, Graeme |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474558/ https://www.ncbi.nlm.nih.gov/pubmed/18307412 http://dx.doi.org/10.1042/BJ20071689 |
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