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Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1

BACKGROUND: As an epigenetic regulator, the transcriptional intermediary factor 1β (TIF1β)/KAP1/TRIM28) has been linked to gene expression and chromatin remodeling at specific loci by association with members of the heterochromatin protein 1 (HP1) family and various other chromatin factors. The inte...

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Detalles Bibliográficos
Autores principales: Chang, Chiung-Wen, Chou, Han-Yi, Lin, Yu-Sheng, Huang, Kuo-Hsiang, Chang, Ching-Jin, Hsu, Tsui-Chun, Lee, Sheng-Chung
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474647/
https://www.ncbi.nlm.nih.gov/pubmed/18590578
http://dx.doi.org/10.1186/1471-2199-9-61