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ATP Release from Vascular Endothelia Occurs Across Cx43 Hemichannels and Is Attenuated during Hypoxia

BACKGROUND: Extracellular ATP is an important signaling molecule for vascular adaptation to limited oxygen availability (hypoxia). Here, we pursued the contribution of vascular endothelia to extracellular ATP release under hypoxic conditions. METHODOLOGY, PRINCIPAL FINDINGS: We gained first insight...

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Detalles Bibliográficos
Autores principales: Faigle, Marion, Seessle, Jessica, Zug, Stephanie, El Kasmi, Karim C., Eltzschig, Holger K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474679/
https://www.ncbi.nlm.nih.gov/pubmed/18665255
http://dx.doi.org/10.1371/journal.pone.0002801