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Comparative 3'UTR Analysis Allows Identification of Regulatory Clusters that Drive Eph/ephrin Expression in Cancer Cell Lines

Eph receptors are the largest family of receptor tyrosine kinases. Together with their ligands, the ephrins, they fulfill multiple biological functions. Aberrant expression of Ephs/ephrins leading to increased Eph receptor to ephrin ligand ratios is a critical factor in tumorigenesis, indicating tha...

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Detalles Bibliográficos
Autores principales: Winter, Jennifer, Roepcke, Stefan, Krause, Sven, Müller, Eva-Christina, Otto, Albrecht, Vingron, Martin, Schweiger, Susann
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474680/
https://www.ncbi.nlm.nih.gov/pubmed/18648668
http://dx.doi.org/10.1371/journal.pone.0002780