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TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation
INTRODUCTION: Signaling downstream of Ras is mediated by three major pathways, Raf/ERK, phosphatidylinositol 3 kinase (PI3K), and Ral guanine nucleotide exchange factor (RalGEF). Ras signal transduction pathways play an important role in breast cancer progression, as evidenced by the frequent over-e...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474852/ https://www.ncbi.nlm.nih.gov/pubmed/18597688 http://dx.doi.org/10.1186/1471-2407-8-189 |