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Retinoic Acid Promotes the Generation of Pancreatic Endocrine Progenitor Cells and Their Further Differentiation into β-Cells

The identification of secreted factors that can selectively stimulate the generation of insulin producing β-cells from stem and/or progenitor cells represent a significant step in the development of stem cell-based β-cell replacement therapy. By elucidating the molecular mechanisms that regulate the...

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Detalles Bibliográficos
Autores principales: Öström, Maria, Loffler, Kelly A., Edfalk, Sara, Selander, Lars, Dahl, Ulf, Ricordi, Camillo, Jeon, Jongmin, Correa-Medina, Mayrin, Diez, Juan, Edlund, Helena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475501/
https://www.ncbi.nlm.nih.gov/pubmed/18665267
http://dx.doi.org/10.1371/journal.pone.0002841