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Retinoic Acid Promotes the Generation of Pancreatic Endocrine Progenitor Cells and Their Further Differentiation into β-Cells
The identification of secreted factors that can selectively stimulate the generation of insulin producing β-cells from stem and/or progenitor cells represent a significant step in the development of stem cell-based β-cell replacement therapy. By elucidating the molecular mechanisms that regulate the...
Autores principales: | Öström, Maria, Loffler, Kelly A., Edfalk, Sara, Selander, Lars, Dahl, Ulf, Ricordi, Camillo, Jeon, Jongmin, Correa-Medina, Mayrin, Diez, Juan, Edlund, Helena |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475501/ https://www.ncbi.nlm.nih.gov/pubmed/18665267 http://dx.doi.org/10.1371/journal.pone.0002841 |
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