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Mdm2 Induces Mono-Ubiquitination of FOXO4
BACKGROUND: The Forkhead box O (FOXO) class of transcription factors are involved in the regulation of several cellular responses including cell cycle progression and apoptosis. Furthermore, in model organisms FOXOs act as tumor suppressors and affect aging. Previously, we noted that FOXOs and p53 a...
Autores principales: | Brenkman, Arjan B., de Keizer, Peter L. J., van den Broek, Niels J. F., Jochemsen, A. G., Burgering, Boudewijn M. Th. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475507/ https://www.ncbi.nlm.nih.gov/pubmed/18665269 http://dx.doi.org/10.1371/journal.pone.0002819 |
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