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Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays
BACKGROUND: Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are k...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475537/ https://www.ncbi.nlm.nih.gov/pubmed/18598341 http://dx.doi.org/10.1186/1471-2164-9-317 |