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Strong position-dependent effects of sequence mismatches on signal ratios measured using long oligonucleotide microarrays

BACKGROUND: Microarrays are an important and widely used tool. Applications include capturing genomic DNA for high-throughput sequencing in addition to the traditional monitoring of gene expression and identifying DNA copy number variations. Sequence mismatches between probe and target strands are k...

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Detalles Bibliográficos
Autores principales: Rennie, Catriona, Noyes, Harry A, Kemp, Stephen J, Hulme, Helen, Brass, Andy, Hoyle, David C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475537/
https://www.ncbi.nlm.nih.gov/pubmed/18598341
http://dx.doi.org/10.1186/1471-2164-9-317