Kinetics and mechanism of K(+)- and Na(+)-induced folding of models of human telomeric DNA into G-quadruplex structures

Cation-induced folding into quadruplex structures for three model human telomeric oligonucleotides, d[AGGG(TTAGGG)(3)], d[TTGGG(TTAGGG)(3)A] and d[TTGGG(TTAGGG)(3)], was characterized by equilibrium titrations with KCl and NaCl and by multiwavelength stopped flow kinetics. Cation binding was coopera...

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Detalles Bibliográficos
Autores principales: Gray, Robert D., Chaires, Jonathan B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475619/
https://www.ncbi.nlm.nih.gov/pubmed/18567908
http://dx.doi.org/10.1093/nar/gkn379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475619/
https://www.ncbi.nlm.nih.gov/pubmed/18567908
http://dx.doi.org/10.1093/nar/gkn379

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