Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

The multisubunit Mediator (MED) complex bridges DNA-bound transcriptional regulators to the RNA polymerase II (PolII) initiation machinery. In yeast, the 25 MED subunits are distributed within three core subcomplexes and a separable kinase module composed of Med12, Med13 and the Cdk8-CycC pair thoug...

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Detalles Bibliográficos
Autor principal: Bourbon, Henri-Marc
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475620/
https://www.ncbi.nlm.nih.gov/pubmed/18515835
http://dx.doi.org/10.1093/nar/gkn349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475620/
https://www.ncbi.nlm.nih.gov/pubmed/18515835
http://dx.doi.org/10.1093/nar/gkn349

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