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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great deal of interest. However, a major issue for oligonucleotide-based therapeutics involves effective intracellular delivery of the active molecules. In this Survey and Summary, we review recent reports...

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Detalles Bibliográficos
Autores principales: Juliano, Rudy, Alam, Md. Rowshon, Dixit, Vidula, Kang, Hyumin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475625/
https://www.ncbi.nlm.nih.gov/pubmed/18558618
http://dx.doi.org/10.1093/nar/gkn342