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TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels
The Wilms tumor gene WT1 encodes a zinc-finger transcription factor that is inactivated in a subset of pediatric kidney cancers. During embryogenesis, WT1 is expressed in a time- and tissue-specific manner in various organs including gonads and kidney but also in the hematopoietic system. Although w...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475629/ https://www.ncbi.nlm.nih.gov/pubmed/18535006 http://dx.doi.org/10.1093/nar/gkn356 |