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TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels

The Wilms tumor gene WT1 encodes a zinc-finger transcription factor that is inactivated in a subset of pediatric kidney cancers. During embryogenesis, WT1 is expressed in a time- and tissue-specific manner in various organs including gonads and kidney but also in the hematopoietic system. Although w...

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Detalles Bibliográficos
Autores principales: Makki, Mohammad Shahidul, Heinzel, Thorsten, Englert, Christoph
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475629/
https://www.ncbi.nlm.nih.gov/pubmed/18535006
http://dx.doi.org/10.1093/nar/gkn356