A motif in the C-terminal domain of ϕC31 integrase controls the directionality of recombination

Bacteriophage ϕC31 encodes an integrase, which acts on the phage and host attachment sites, attP and attB, to form an integrated prophage flanked by attL and attR. In the absence of accessory factors, ϕC31 integrase cannot catalyse attL x attR recombination to excise the prophage. To understand the...

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Detalles Bibliográficos
Autores principales: Rowley, Paul A., Smith, Matthew C. A., Younger, Ellen, Smith, Margaret C. M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475636/
https://www.ncbi.nlm.nih.gov/pubmed/18502775
http://dx.doi.org/10.1093/nar/gkn269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475636/
https://www.ncbi.nlm.nih.gov/pubmed/18502775
http://dx.doi.org/10.1093/nar/gkn269

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