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Intramolecular Cohesion of Coils Mediated by Phenylalanine–Glycine Motifs in the Natively Unfolded Domain of a Nucleoporin

The nuclear pore complex (NPC) provides the sole aqueous conduit for macromolecular exchange between the nucleus and the cytoplasm of cells. Its diffusion conduit contains a size-selective gate formed by a family of NPC proteins that feature large, natively unfolded domains with phenylalanine–glycin...

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Detalles Bibliográficos
Autores principales: Krishnan, V. V., Lau, Edmond Y., Yamada, Justin, Denning, Daniel P., Patel, Samir S., Colvin, Michael E., Rexach, Michael F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475668/
https://www.ncbi.nlm.nih.gov/pubmed/18688269
http://dx.doi.org/10.1371/journal.pcbi.1000145