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Targeted Disruption of NeuroD, a Proneural Basic Helix-Loop-Helix Factor, Impairs Distal Lung Formation and Neuroendocrine Morphology in the Neonatal Lung

Despite the importance of airspace integrity in vertebrate gas exchange, the molecular pathways that instruct distal lung formation are poorly understood. Recently, we found that fibrillin-1 deficiency in mice impairs alveolar formation and recapitulates the pulmonary features of human Marfan syndro...

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Detalles Bibliográficos
Autores principales: Neptune, Enid R., Podowski, Megan, Calvi, Carla, Cho, Jang-Hyeon, Garcia, Joe G. N., Tuder, Rubin, Linnoila, R. Ilona, Tsai, Ming-Jer, Dietz, Harry C.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475704/
https://www.ncbi.nlm.nih.gov/pubmed/18339630
http://dx.doi.org/10.1074/jbc.M708692200