A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

Hepatocyte growth factor (HGF) and its high affinity receptor, the tyrosine kinase Met, play a key role in embryo development and tumor invasion. Both HGF and Met are established targets for cancer therapy. However, the mechanism of their interaction is complex and remains elusive. HGF is secreted a...

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Detalles Bibliográficos
Autores principales: Basilico, Cristina, Arnesano, Addolorata, Galluzzo, Maria, Comoglio, Paolo M., Michieli, Paolo
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475716/
https://www.ncbi.nlm.nih.gov/pubmed/18495663
http://dx.doi.org/10.1074/jbc.M800727200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475716/
https://www.ncbi.nlm.nih.gov/pubmed/18495663
http://dx.doi.org/10.1074/jbc.M800727200

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