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Streptozotocin and Alloxan-based Selection Improves Toxin Resistance of Insulin-Producing RINm Cells
The aim of our study was to develop a method for selection of subpopulations of insulin producing RINm cells with higher resistance to beta cell toxins. Cells, resistant to streptozotocin (RINmS) and alloxan (RINmA), were obtained by repeated exposure of parental RINm cells to these two toxins, whil...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477732/ https://www.ncbi.nlm.nih.gov/pubmed/11467412 http://dx.doi.org/10.1155/EDR.2000.211 |