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Defective Morphogenesis and Functional Maturation in Fetal Islet-Like Cell Clusters From OLETF Rat, A Model of NIDDM

A failure in the compensate proliferation of pancreatic β-cells, as the primary pathogenic event, has been reported in OLETF rat, a model of NIDDM. The aim of the present study is to define whether the β-cell defect is attributed to the fetal stage islet development, if so, whether the defect involv...

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Detalles Bibliográficos
Autores principales: Zhu, Min, Mizuno, Akira, Noma, Yoshihiko, Murakami, Takashi, Kuwajima, Masamichi, Shima, Kenji, Lan, Michael S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2477740/
https://www.ncbi.nlm.nih.gov/pubmed/11467419
http://dx.doi.org/10.1155/EDR.2000.289