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Glucose-dependent and Glucose-sensitizing Insulinotropic Effect of Nateglinide: Comparison to Sulfonylureas and Repaglinide
Nateglinide, a novel D-phenylalanine derivative, stimulates insulin release via closure of K(ATP) channels in pancreatic β-cell, a primary mechanism of action it shares with sulfonylureas (SUs) and repaglinide. This study investigated (1) the influence of ambient glucose levels on the insulinotropic...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478524/ https://www.ncbi.nlm.nih.gov/pubmed/12369728 http://dx.doi.org/10.1155/EDR.2001.63 |