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Effectiveness of Nateglinide on In Vitro Insulin Secretion from Rat Pancreatic Islets Desensitized to Sulfonylureas
Chronic exposure of pancreatic islets to sulfonylureas (SUs) is known to impair the ability of islets to respond to subsequent acute stimulation by SUs or glucose. Nateglinide (NAT) is a novel insulinotropic agent with a primarily site of action at β-cell K(ATP) channels, which is common to the stru...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478527/ https://www.ncbi.nlm.nih.gov/pubmed/12369729 http://dx.doi.org/10.1155/EDR.2001.73 |