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Approaches to Type 1 Diabetes Prevention by Intervention in Cytokine Immunoregulatory Circuits
Type 1 (insulin-dependent) diabetes mellitus, like other organ specific autoimmune diseases, results from a disorder of immunoregulation. T cells specific for pancreatic islet ß cell constituents (autoantigens) exist normally but are restrained by regulatory mechanisms (self-tolerant state). When re...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478533/ https://www.ncbi.nlm.nih.gov/pubmed/12369724 http://dx.doi.org/10.1155/EDR.2001.3 |