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C-Peptide Prevents Hippocampal Apoptosis in Type 1 Diabetes

To explore mechanisms underlying central nervous system (CNS) complications in diabetes, we examined hippocampal neuronal apoptosis and loss, and the effect of C-peptide replacement in type 1 diabetic BB/W rats. Apoptosis was demonstrated after 8 months of diabetes, by DNA fragmentation, increased n...

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Detalles Bibliográficos
Autores principales: Li, Zhen-guo, Zhang, Weixian, Sima, Anders A. F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478591/
https://www.ncbi.nlm.nih.gov/pubmed/12546277
http://dx.doi.org/10.1080/15604280214936