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Knockout Mice Challenge our Concepts of Glucose Homeostasis and the Pathogenesis of Diabetes
A central component of type 2 diabetes and the metabolic syndrome is insulin resistance. Insulin exerts a multifaceted and highly integrated series of actions via its intracellular signaling systems. Generation of mice carrying null mutations of the genes encoding proteins in the insulin signaling p...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478605/ https://www.ncbi.nlm.nih.gov/pubmed/15061645 http://dx.doi.org/10.1155/EDR.2003.169 |