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The Proinsulin C-peptide—A Multirole Model

The C-peptide links the insulin A and B chains in proinsulin, providing thereby a means to promote their efficient folding and assembly in the endoplasmic reticulum during insulin biosynthesis. It then facilitates the intracellular transport, sorting, and proteolytic processing of proinsulin into bi...

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Detalles Bibliográficos
Autor principal: Steiner, Donald F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478623/
https://www.ncbi.nlm.nih.gov/pubmed/15198367
http://dx.doi.org/10.1080/15438600490424389