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The Proinsulin C-peptide—A Multirole Model
The C-peptide links the insulin A and B chains in proinsulin, providing thereby a means to promote their efficient folding and assembly in the endoplasmic reticulum during insulin biosynthesis. It then facilitates the intracellular transport, sorting, and proteolytic processing of proinsulin into bi...
Autor principal: | Steiner, Donald F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478623/ https://www.ncbi.nlm.nih.gov/pubmed/15198367 http://dx.doi.org/10.1080/15438600490424389 |
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