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Improved Experimental Procedures for Achieving Efficient Germ Line Transmission of Nonobese Diabetic (NOD)-Derived Embryonic Stem Cells

The manipulation of a specific gene in NOD mice, the best animal model for insulin-dependent diabetes mellitus (IDDM), must allow for the precise characterization of the functional involvement of its encoded molecule in the pathogenesis of the disease. Although this has been attempted by the cross-b...

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Detalles Bibliográficos
Autores principales: Arai, Satoko, Minjares, Christina, Nagafuchi, Seiho, Miyazaki, Toru
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478631/
https://www.ncbi.nlm.nih.gov/pubmed/15512790
http://dx.doi.org/10.1080/15438600490486877