Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes

The sterol regulatory element-binding protein (SREBP) family member SREBP1 is a critical transcriptional regulator of cholesterol and fatty acid metabolism and has been implicated in insulin resistance, diabetes, and other diet-related diseases. We globally identified the promoters occupied by SREBP...

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Detalles Bibliográficos
Autores principales: Reed, Brian D., Charos, Alexandra E., Szekely, Anna M., Weissman, Sherman M., Snyder, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478640/
https://www.ncbi.nlm.nih.gov/pubmed/18654640
http://dx.doi.org/10.1371/journal.pgen.1000133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478640/
https://www.ncbi.nlm.nih.gov/pubmed/18654640
http://dx.doi.org/10.1371/journal.pgen.1000133

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