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The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency

BACKGROUND: Genetic variation may underlie phenotypic variation in chronic obstructive pulmonary disease (COPD) in subjects with and without alpha 1 antitrypsin deficiency (AATD). Genotype specific sub-phenotypes are likely and may underlie the poor replication of previous genetic studies. This stud...

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Detalles Bibliográficos
Autores principales: Wood, Alice M, Simmonds, Matthew J, Bayley, Darren L, Newby, Paul R, Gough, Stephen C, Stockley, Robert A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478658/
https://www.ncbi.nlm.nih.gov/pubmed/18620570
http://dx.doi.org/10.1186/1465-9921-9-52