The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells

BACKGROUND: Most cases of colorectal cancer are initiated by hyperactivation of the Wnt/β-catenin pathway due to mutations in the APC tumour suppressor, or in β-catenin itself. A recently discovered component of this pathway is Legless, which is essential for Wnt-induced transcription during Drosoph...

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Detalles Bibliográficos
Autores principales: de la Roche, Marc, Worm, Jesper, Bienz, Mariann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478683/
https://www.ncbi.nlm.nih.gov/pubmed/18627596
http://dx.doi.org/10.1186/1471-2407-8-199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478683/
https://www.ncbi.nlm.nih.gov/pubmed/18627596
http://dx.doi.org/10.1186/1471-2407-8-199

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