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The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells
BACKGROUND: Most cases of colorectal cancer are initiated by hyperactivation of the Wnt/β-catenin pathway due to mutations in the APC tumour suppressor, or in β-catenin itself. A recently discovered component of this pathway is Legless, which is essential for Wnt-induced transcription during Drosoph...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478683/ https://www.ncbi.nlm.nih.gov/pubmed/18627596 http://dx.doi.org/10.1186/1471-2407-8-199 |