Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants

BACKGROUND: Some of the biochemical events that lead to necrosis of the liver are well-known. However, the pathogenesis of necrosis of the liver from exposure to hepatotoxicants is a complex biological response to the injury. We hypothesize that gene expression profiles can serve as a signature to p...

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Detalles Bibliográficos
Autores principales: Huang, Lingkang, Heinloth, Alexandra N, Zeng, Zhao-Bang, Paules, Richard S, Bushel, Pierre R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478688/
https://www.ncbi.nlm.nih.gov/pubmed/18558008
http://dx.doi.org/10.1186/1471-2164-9-288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478688/
https://www.ncbi.nlm.nih.gov/pubmed/18558008
http://dx.doi.org/10.1186/1471-2164-9-288

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