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Emergence of Xin Demarcates a Key Innovation in Heart Evolution

The mouse Xin repeat-containing proteins (mXinα and mXinβ) localize to the intercalated disc in the heart. mXinα is able to bundle actin filaments and to interact with β-catenin, suggesting a role in linking the actin cytoskeleton to N-cadherin/β-catenin adhesion. mXinα-null mouse hearts display pro...

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Detalles Bibliográficos
Autores principales: Grosskurth, Shaun E., Bhattacharya, Debashish, Wang, Qinchuan, Lin, Jim Jung-Ching
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478706/
https://www.ncbi.nlm.nih.gov/pubmed/18682726
http://dx.doi.org/10.1371/journal.pone.0002857