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High-Throughput Isolation and Mapping of C. elegans Mutants Susceptible to Pathogen Infection

We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C. elegans mutants that exhibit an enhanced pathogen accumulation (epa) phenotype can be rapidly identified and isolated using a sorting system th...

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Detalles Bibliográficos
Autores principales: Fuhrman, Laura E., Shianna, Kevin V., Aballay, Alejandro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478710/
https://www.ncbi.nlm.nih.gov/pubmed/18682730
http://dx.doi.org/10.1371/journal.pone.0002882