A High-Sensitivity Method for Detection and Measurement of HMGB1 Protein Concentration by High-Affinity Binding to DNA Hemicatenanes

BACKGROUND: Protein HMGB1, an abundant nuclear non-histone protein that interacts with DNA and has an architectural function in chromatin, was strikingly shown some years ago to also possess an extracellular function as an alarmin and a mediator of inflammation. This extracellular function has since...

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Detalles Bibliográficos
Autores principales: Gaillard, Claire, Borde, Chloé, Gozlan, Joël, Maréchal, Vincent, Strauss, François
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478715/
https://www.ncbi.nlm.nih.gov/pubmed/18682735
http://dx.doi.org/10.1371/journal.pone.0002855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478715/
https://www.ncbi.nlm.nih.gov/pubmed/18682735
http://dx.doi.org/10.1371/journal.pone.0002855

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