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Mitochondrial Targeting Adaptation of the Hominoid-Specific Glutamate Dehydrogenase Driven by Positive Darwinian Selection

Many new gene copies emerged by gene duplication in hominoids, but little is known with respect to their functional evolution. Glutamate dehydrogenase (GLUD) is an enzyme central to the glutamate and energy metabolism of the cell. In addition to the single, GLUD-encoding gene present in all mammals...

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Detalles Bibliográficos
Autores principales: Rosso, Lia, Marques, Ana C., Reichert, Andreas S., Kaessmann, Henrik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478720/
https://www.ncbi.nlm.nih.gov/pubmed/18688271
http://dx.doi.org/10.1371/journal.pgen.1000150