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Irradiation leads to apoptosis of Kupffer cells by a Hsp27-dependant pathway followed by release of TNF-α

In a previous publication, we were able to show that irradiation of Kupffer cells, the liver resident macrophages, leads to an increased TNF-α concentration in the culture medium. The pathomechanisms underlying this phenomenon, however, remained to be elucidated. Here, we show that following irradia...

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Detalles Bibliográficos
Autores principales: Tello, K., Christiansen, H., Gürleyen, H., Dudas, J., Rave-Fränk, M., Hess, C. F., Ramadori, G., Saile, B.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480490/
https://www.ncbi.nlm.nih.gov/pubmed/18493784
http://dx.doi.org/10.1007/s00411-008-0170-3