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Modulation of the conductance of a 2,2′-bipyridine-functionalized peptidic ion channel by Ni(2+)

An α-helical amphipathic peptide with the sequence H(2)N-(LSSLLSL)(3)-CONH(2) was obtained by solid phase synthesis and a 2,2′-bipyridine was coupled to its N-terminus, which allows complexation of Ni(2+). Complexation of the 2,2′-bipyridine residues was proven by UV/Vis spectroscopy. The peptide he...

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Detalles Bibliográficos
Autores principales: Pilz, Claudia S., Steinem, Claudia
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480505/
https://www.ncbi.nlm.nih.gov/pubmed/18347789
http://dx.doi.org/10.1007/s00249-008-0298-8