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Modulation of the conductance of a 2,2′-bipyridine-functionalized peptidic ion channel by Ni(2+)
An α-helical amphipathic peptide with the sequence H(2)N-(LSSLLSL)(3)-CONH(2) was obtained by solid phase synthesis and a 2,2′-bipyridine was coupled to its N-terminus, which allows complexation of Ni(2+). Complexation of the 2,2′-bipyridine residues was proven by UV/Vis spectroscopy. The peptide he...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2480505/ https://www.ncbi.nlm.nih.gov/pubmed/18347789 http://dx.doi.org/10.1007/s00249-008-0298-8 |