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The role of upstream sequences in selecting the reading frame on tmRNA

BACKGROUND: tmRNA acts first as a tRNA and then as an mRNA to rescue stalled ribosomes in eubacteria. Two unanswered questions about tmRNA function remain: how does tmRNA, lacking an anticodon, bypass the decoding machinery and enter the ribosome? Secondly, how does the ribosome choose the proper co...

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Detalles Bibliográficos
Autores principales: Miller, Mickey R, Healey, David W, Robison, Stephen G, Dewey, Jonathan D, Buskirk, Allen R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481249/
https://www.ncbi.nlm.nih.gov/pubmed/18590561
http://dx.doi.org/10.1186/1741-7007-6-29